285 research outputs found

    Exact eigenspectrum of the symmetric simple exclusion process on the complete, complete bipartite, and related graphs

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    We show that the infinitesimal generator of the symmetric simple exclusion process, recast as a quantum spin-1/2 ferromagnetic Heisenberg model, can be solved by elementary techniques on the complete, complete bipartite, and related multipartite graphs. Some of the resulting infinitesimal generators are formally identical to homogeneous as well as mixed higher spins models. The degeneracies of the eigenspectra are described in detail, and the Clebsch-Gordan machinery needed to deal with arbitrary spin-s representations of the SU(2) is briefly developed. We mention in passing how our results fit within the related questions of a ferromagnetic ordering of energy levels and a conjecture according to which the spectral gaps of the random walk and the interchange process on finite simple graphs must be equal.Comment: Final version as published, 19 pages, 4 figures, 40 references given in full forma

    Unification of Dark Matter and Dark Energy in a Modified Entropic Force Model

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    In Verlinde's entropic force scenario of gravity, Newton's laws and Einstein equations can be obtained from the first pinciples and general assumptions. However, the equipartition law of energy is invalid at very low temperatures. We show clearly that the threshold of the equipartition law of energy is related with horizon of the universe. Thus, a one-dimension Debye (ODD) model in the direction of radius of the modified entropic force (MEF) maybe suitable in description of the accelerated expanding universe. We present a Friedmann cosmic dynamical model in the ODD-MEF framework. We examine carefully constraints on the ODD-MEF model from the Union2 compilation of the Supernova Cosmology Project (SCP) collaboration, the data from the observation of the large-scale structure (LSS) and the cosmic microwave background (CMB), i.e. SNe Ia+LSS+CMB. The combined numerical analysis gives the best-fit value of the model parameters ζ109\zeta\simeq10^{-9} and Ωm0=0.224\Omega_{m0}=0.224, with χmin2=591.156\chi_{min}^2=591.156. The corresponding age of the universe agrees with the result of D. Spergel {\it et al.}\cite{Spergel2003} at 95% confidence level. The numerical result also yields an accelerated expanding universe without invoking any kind of dark energy. Taking ζ(2πωD/H0)\zeta(\equiv 2\pi \omega_D/H_0) as a running parameter associated with the structure scale rr, we obtain a possible unified scenario of the asymptotic flatness of the radial velocity dispersion of spiral galaxies, the accelerated expanding universe and the Pioneer 10/11 anomaly in the entropic force framework of Verlinde.Comment: 23 pages, 6 figure

    Endorsement of the CONSORT Statement by High-Impact Medical Journals in China: A Survey of Instructions for Authors and Published Papers

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    The CONSORT Statement is a reporting guideline for authors when reporting randomized controlled trials (RCTs). It offers a standard way for authors to prepare RCT reports. It has been endorsed by many high-impact medical journals and by international editorial groups. This study was conducted to assess the endorsement of the CONSORT Statement by high-impact medical journals in China by reviewing their instructions for authors.A total of 200 medical journals were selected according to the Chinese Science and Technology Journal Citation Reports, 195 of which publish clinical research papers. Their instructions for authors were reviewed and all texts mentioning the CONSORT Statement or CONSORT extension papers were extracted. Any mention of the Uniform Requirements for Manuscripts Submitted to Biomedical Journals (URM) developed by the International Committee of Medical Journal Editors (ICMJE) or ‘clinical trial registration’ was also extracted. For journals endorsing the CONSORT Statement, their most recently published RCT reports were retrieved and evaluated to assess whether the journals have followed what the CONSORT Statement required. Out of the 195 medical journals publishing clinical research papers, only six (6/195, 3.08%) mentioned ‘CONSORT’ in their instructions for authors; out of the 200 medical journals surveyed, only 14 (14/200, 7.00%) mentioned ‘ICMJE’ or ‘URM’ in their instructions for authors, and another five journals stated in their instructions for authors that clinical trials should have trial registration numbers and that priority would be given to clinical trials which had been registered. Among the 62 RCT reports published in the six journals endorsing the CONSORT Statement, 20 (20/62, 32.26%) contained flow diagrams and only three (3/62, 4.84%) provided trial registration information.Medical journals in China endorsing either the CONSORT Statement or the ICMJE's URM constituted a small percentage of the total; all of these journals used ambiguous language regarding what was expected of authors

    A Roadmap for Astrophysics and Cosmology with High-Redshift 21 cm Intensity Mapping

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    In this white paper, we lay out a US roadmap for high-redshift 21 cm cosmology (30 < z < 6) in the 2020s. Beginning with the currently-funded HERA and MWA Phase II projects and advancing through the decade with a coordinated program of small-scale instrumentation, software, and analysis projects targeting technology development, this roadmap incorporates our current best understanding of the systematics confronting 21 cm cosmology into a plan for overcoming them, enabling next-generation, mid-scale 21 cm arrays to be proposed late in the decade. Submitted for consideration by the Astro2020 Decadal Survey Program Panel for Radio, Millimeter, and Submillimeter Observations from the Ground as a Medium-Sized Project.Comment: 10 pages (plus a cover page and references), 6 figures. Submitted as a APC White Paper for Astro202

    A Note on the Path Integral Representation of the Boundary State of D-brane

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    In this paper we construct path integral representations of the boundary states in some special backgrounds such as the U(1) gauge field background, the linear dilaton background and the open string tachyon background. The initial purpose of this paper is to construct a general solution of the boundary conformal field theory with the analytical approach, mainly for the constraint equations(LnL~n)B>=0(L_{n}-\tilde{L}_{-n}) |B > =0 are difficult to be solved to obtain the solution represented by string modes from the pure algebraic approach. However in the path integral representation it is easy transforming those algebraic equations into the differential equations which can be solved. Another purpose of this paper is to try to explore an open question. we do not know how to construct an exact theory of D-branes in the general background until now. However many recent researches show the boundary state description indeed seizes some fundamental features of D-branes in the rather special backgrounds. Since the general background field effects can be easily introduced in the path integral representation, we argue that path integral representation of the boundary state should provide an exact description of D branes in the general backgrounds.Comment: 21 pages, no figure,Latex. v2:minor modification, references added. v3: 23 pages, AMSLaTeX using JHEP.cls, v3 is one part of my Master thesi

    An overview of digital speech watermarking

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    Digital speech watermarking is a robust way to hide and thus secure data like audio and video from any intentional or unintentional manipulation through transmission. In terms of some signal characteristics including bandwidth, voice/non-voice and production model, digital speech signal is different from audio, music and other signals. Although, various review articles on image, audio and video watermarking are available, there are still few review papers on digital speech watermarking. Therefore this article presents an overview of digital speech watermarking including issues of robustness, capacity and imperceptibility. Other issues discussed are types of digital speech watermarking, application, models and masking methods. This article further highlights the related challenges in the real world, research opportunities and future works in this area, yet to be explored fully

    Significance of Aurora B overexpression in hepatocellular carcinoma. Aurora B Overexpression in HCC

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    <p>Abstract</p> <p>Background</p> <p>To investigate the significance of Aurora B expression in hepatocellular carcinoma (HCC).</p> <p>Methods</p> <p>The <it>Aurora B </it>and <it>Aurora A </it>mRNA level was measured in 160 HCCs and the paired nontumorous liver tissues by reverse transcription-polymerase chain reaction. Mutations of the <it>p53 </it>and <it>β-catenin </it>genes were analyzed in 134 and 150 tumors, respectively, by direct sequencing of exon 2 to exon 11 of <it>p53 </it>and exon 3 of <it>β-catenin</it>. Anticancer effects of AZD1152-HQPA, an Aurora B kinase selective inhibitor, were examined in Huh-7 and Hep3B cell lines.</p> <p>Results</p> <p><it>Aurora B </it>was overexpressed in 98 (61%) of 160 HCCs and in all 7 HCC cell lines examined. The overexpression of <it>Aurora B </it>was associated with <it>Aurora A </it>overexpression (<it>P </it>= 0.0003) and <it>p53 </it>mutation (<it>P </it>= 0.002) and was inversely associated with <it>β</it>-<it>catenin </it>mutation (<it>P </it>= 0.002). <it>Aurora B </it>overexpression correlated with worse clinicopathologic characteristics. Multivariate analysis confirmed that <it>Aurora B </it>overexpression was an independent poor prognostic factor, despite its interaction with Aurora A overexpression and mutations of <it>p53 </it>and <it>β</it>-<it>catenin</it>. In Huh-7 and Hep3B cells, AZD1152-HQPA induced proliferation blockade, histone H3 (Ser10) dephosphorylation, cell cycle disturbance, and apoptosis.</p> <p>Conclusion</p> <p><it>Aurora B </it>overexpression is an independent molecular marker predicting tumor invasiveness and poor prognosis of HCC. Aurora B kinase selective inhibitors are potential therapeutic agents for HCC treatment.</p

    An Inflationary Scenario Taking into Account of Possible Dark Energy Effects in the Early Universe

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    We investigate the possible effect of cosmological-constant type dark energy during the inflation period of the early universe. This is accommodated by a new dispersion relation in de Sitter space. The modified inflation model of a minimally-coupled scalar field is still able to yield an observation-compatible scale-invariant primordial spectrum, simultaneously having potential to generate a spectrum with lower power at large scales. A qualitative match to the WMAP 7-year data is presented. We obtain an ΩΛ\Omega_\Lambda of the same order of that in the Λ\Lambda-CDM model. Possible relations between the de Sitter scenario and the Doubly Special Relativity(DSR) are also discussed.Comment: 17 pages, 3 figuire
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